Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.37 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.37 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361771 | 1.00 | MAPT (0.47) | MAPTDRD4HRH2PDK1PDK2 | |
| SCHEMBL13059797 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL13059798 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL3540797 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL4072294 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL13985605 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL3535329 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL3536137 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL3538785 | 0.84 | MAPT (0.50) | MAPTHRH2PDK1PDK2PDK3 | |
| SCHEMBL31024632 | 0.84 | DRD4 (0.41) | DRD4SIGMAR1CHI3L1CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173453-A1 | HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |