SCHEMBL31050996

SCHEMBL31050996

CCOC(=O)C(C)(C)CNC(=O)c1ncc(-c2cn(CCCc3ccc(Cl)cc3)nn2)cc1O

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25278826 1.00 EGLN1 (0.69) EGLN1
SCHEMBL25280336 0.90 EGLN1 (0.77) EGLN1
SCHEMBL25934719 0.83 EGLN1 (0.85) EGLN1
SCHEMBL23562801 0.82 EGLN1 (1.00) EGLN1
SCHEMBL24257803 0.75 EGLN1 (0.57) EGLN1
Glycine SCHEMBL28393884 0.75 EGLN1 (0.73) EGLN1
SCHEMBL31051010 0.75 EGLN1 (0.53) EGLN1
SCHEMBL30457525 0.75 EGLN1 (0.53) EGLN1
SCHEMBL25279438 0.75 EGLN1 (0.53) EGLN1
SCHEMBL25692419 0.73 EGLN1 (0.39) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118715015-A Selective PHD1 inhibitor compounds, compositions and methods of use 阿克比治疗有限公司 2024-09-27 CN disclosed