Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051343 | 1.00 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL31051355 | 0.91 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL30822795 | 0.90 | TLR8 (0.76) | TLR8TLR7 | |
| SCHEMBL24699639 | 0.89 | TLR8 (0.71) | TLR8TLR7 | |
| SCHEMBL30822808 | 0.87 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL24699640 | 0.87 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL24699319 | 0.82 | TLR8 (0.55) | TLR8TLR7 | |
| SCHEMBL19651888 | 0.81 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19641804 | 0.81 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL27078390 | 0.81 | TLR8 (0.43) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299569-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299569-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | AADAC, BRD4, IDO2 | TLR8 3049/4885TLR7 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.