Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 1.00 |
| ▸ | DRD3 | P35462 | 9/20 | 1.00 |
| ▸ | DRD1 | P21728 | 4/20 | 1.00 |
| ▸ | HTR2A | P28223 | 4/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 1.00 |
| ▸ | DRD4 | P21917 | 6/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052127 | 0.81 | DRD2 (0.73) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051863 | 0.80 | DRD2 (0.67) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051854 | 0.80 | DRD2 (0.67) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051932 | 0.80 | DRD2 (1.00) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051808 | 0.80 | DRD2 (0.71) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051724 | 0.80 | DRD2 (0.67) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051828 | 0.80 | DRD2 (0.71) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL7814738 | 0.80 | DRD2 (0.67) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051887 | 0.80 | DRD2 (0.66) | DRD2DRD3DRD1HTR2ASIGMAR1 | |
| SCHEMBL31051880 | 0.79 | DRD2 (0.65) | DRD2DRD3DRD1HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678188-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | Ohnishi, Arata (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024185842-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING, OR MANAGING BILIRUBIN-INDUCED NEUROLOGICAL DYSFUNCTION, PSYCHIATRIC DISORDERS ASSOCIATED WITH JAUNDICE, OR PSYCHIATRIC DISORDERS CAUSED BY BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS | 国立大学法人島根大学 | 2024-09-12 | — | — | WO | disclosed |