Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.57 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.47 |
| ▸ | BRAF | P15056 | 5/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052822 | 0.86 | GRN (0.42) | GRNSORT1ITGB1ITGA4CYP2C19 | |
| SCHEMBL31052839 | 0.80 | GRN (0.57) | GRNSORT1ITGB1ITGA4BRAF | |
| SCHEMBL31052825 | 0.78 | SORT1 (0.44) | GRNSORT1ITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL27165513 | 0.76 | GRN (0.55) | GRNSORT1 | |
| SCHEMBL27165674 | 0.76 | GRN (0.55) | GRNSORT1 | |
| SCHEMBL31052773 | 0.74 | GRN (0.46) | GRNSORT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31052775 | 0.74 | GRN (0.52) | GRNSORT1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL31052893 | 0.73 | ITGAV (0.44) | GRNSORT1KDRCYP2C9 | |
| SCHEMBL25273962 | 0.72 | SORT1 (1.00) | GRNSORT1CYP2C9 | |
| SCHEMBL31601087 | 0.72 | GRN (0.67) | GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | claimed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | claimed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | claimed |
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | disclosed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | disclosed |