Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052804 | 0.86 | GRN (0.53) | MAPTMAPK1KDM4ENPSR1HPGD | |
| SCHEMBL5151065 | 0.73 | NLRP3 (0.40) | MAPTMAPK1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL14433844 | 0.72 | MAPT (0.49) | MAPTMAPK1KDM4ENPSR1HTT | |
| SCHEMBL3790245 | 0.71 | HPGD (0.63) | MAPTMAPK1HPGDALOX15HTT | |
| SCHEMBL9132938 | 0.70 | MAPT (0.46) | MAPTHPGDALOX15HTTMEN1 | |
| SCHEMBL1531481 | 0.70 | MAPK1 (0.56) | MAPTMAPK1KDM4ENPSR1HPGD | |
| SCHEMBL1531484 | 0.70 | MAPK1 (0.56) | MAPTMAPK1KDM4ENPSR1HPGD | |
| SCHEMBL31052824 | 0.69 | GRN (0.48) | MAPTMAPK1HPGDGRNSORT1 | |
| SCHEMBL8224241 | 0.69 | MAPT (0.50) | MAPTMAPK1HPGDALOX15HTT | |
| SCHEMBL11171997 | 0.69 | MAPT (0.54) | MAPTMAPK1KDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676914-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184469-A1 | MODULATORS OF SORTILIN ACTIVITY | VESPER BIO APS (DK) | 2024-09-12 | — | — | WO | disclosed |
| EP-4428121-A1 | MODULATORS OF SORTILIN ACTIVITY | Vesper Bio Aps (DK) | 2024-09-11 | — | — | EP | disclosed |