Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 13/20 | 0.66 |
| ▸ | TUBB | P07437 | 13/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.66 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.66 |
| ▸ | EGFR | P00533 | 6/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.66 |
| ▸ | KDR | P35968 | 5/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053027 | 0.89 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053033 | 0.88 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053040 | 0.87 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053042 | 0.85 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16622677 | 0.84 | TUBB4A (0.89) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053036 | 0.82 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053032 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053039 | 0.79 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16622703 | 0.79 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31053030 | 0.79 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561818-A | Diaryl substituted 2, 3-indoline compound or medicinal salt thereof, preparation method and application thereof | 河南大学 | 2024-08-30 | — | — | CN | disclosed |