Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 15/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | PRNP | P04156 | 3/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.67 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550085 | 1.00 | ACMSD (1.00) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL26847147 | 0.92 | ACMSD (0.85) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053416 | 0.92 | ACMSD (0.85) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23849892 | 0.92 | ACMSD (0.85) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL17548496 | 0.89 | ACMSD (1.00) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053422 | 0.89 | ACMSD (1.00) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053424 | 0.87 | ACMSD (0.76) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23849818 | 0.87 | ACMSD (0.76) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL31053420 | 0.86 | ACMSD (0.78) | ACMSDCYP2C19MEN1KMT2APRNP | |
| SCHEMBL23850316 | 0.86 | ACMSD (0.78) | ACMSDCYP2C19MEN1KMT2APRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240882-A1 | HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR USE IN TREATING ACUTE INFLAMMATION | TES PHARMA S.R.L. (IT) | 2024-11-28 | — | — | WO | disclosed |
| CN-118496217-A | Inhibitors of alpha-amino-beta-carboxyhexadienoic acid semialdehyde decarboxylase | TES制药有限责任公司 | 2024-08-16 | — | — | CN | disclosed |