Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 1.00 |
| ▸ | MIF | P14174 | 4/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KIT | P10721 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobonducellin SCHEMBL31238399 | 1.00 | MAOB (1.00) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL29837280 | 0.88 | MIF (1.00) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL5725497 | 0.86 | MAPT (0.77) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL30274371 | 0.85 | CXCL12 (0.80) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL14160665 | 0.85 | MAPT (0.82) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL25035409 | 0.85 | CXCL12 (0.80) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL5726073 | 0.84 | MAOB (0.72) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| Sappanone A 7-Methyl Ether SCHEMBL14479894 | 0.83 | MAPT (1.00) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL8785149 | 0.82 | MAOB (0.73) | MAOBMIFCYP3A4MAPTALDH1A1 | |
| SCHEMBL8785142 | 0.82 | MAOB (0.73) | MAOBMIFCYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118634256-A | Preparation method of holly extract | 浙江理工大学绍兴生物医药研究院有限公司 | 2024-09-13 | — | — | CN | disclosed |