Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.72 |
| ▸ | MIF | P14174 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725497 | 0.91 | MAPT (0.77) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL14160665 | 0.90 | MAPT (0.82) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL30274371 | 0.88 | CXCL12 (0.80) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL25035409 | 0.88 | CXCL12 (0.80) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL5725448 | 0.85 | MAOB (0.67) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL5724831 | 0.85 | MAOB (0.67) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| Bonducellin SCHEMBL31053952 | 0.84 | MAOB (1.00) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| Isobonducellin SCHEMBL31238399 | 0.84 | MAOB (1.00) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL8465775 | 0.82 | APP (0.79) | MAOBMIFMAPTALDH1A1CYP3A4 | |
| SCHEMBL8465773 | 0.82 | APP (0.79) | MAOBMIFMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080781-A | Tetralone or benzopyranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-06-27 | — | — | US | claimed |
| EP-0902003-B1 | NOVEL TETRALONE OR BENZOPYRANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6080781-A | Tetralone or benzopyranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0902003-A1 | NOVEL TETRALONE OR BENZOPYRANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |