Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055425 | 0.87 | HTT (0.55) | GAAKMT2AHPGDKDM4EHTT | |
| SCHEMBL26833241 | 0.86 | KMT2A (0.43) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL31055454 | 0.85 | PREP (0.45) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL21805763 | 0.85 | PREP (0.46) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL3298856 | 0.84 | KMT2A (0.56) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL26763903 | 0.83 | KMT2A (0.61) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL31055431 | 0.80 | ADORA2A (0.50) | KDM4EHTTLMNACNR2SMN1; SMN2 | |
| SCHEMBL5263362 | 0.80 | KMT2A (0.41) | GAAKMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL3299192 | 0.78 | HPGD (0.51) | KMT2AHPGDKDM4EHTTALDH1A1 | |
| SCHEMBL3033385 | 0.78 | HPGD (0.55) | KMT2AHPGDKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |