Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469331 | 0.86 | LOXL2 (0.51) | PREPLMNASMN1; SMN2HTTCA12 | |
| SCHEMBL25307043 | 0.82 | PREP (0.45) | ADORA2APREPCNR2LMNASMN1; SMN2 | |
| SCHEMBL31055445 | 0.80 | GAA (0.59) | PREPCNR2LMNASMN1; SMN2HTT | |
| SCHEMBL3299192 | 0.79 | HPGD (0.51) | PREPHTTL3MBTL1KDM1AHDAC1 | |
| SCHEMBL3033385 | 0.79 | HPGD (0.55) | L3MBTL1NPC1KDM4EALDH1A1 | |
| SCHEMBL31055425 | 0.79 | HTT (0.55) | CNR1LMNASMN1; SMN2HTTNAMPT | |
| SCHEMBL2998198 | 0.78 | KDM4E (0.55) | PREPLMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL31638112 | 0.78 | HDAC6 (0.50) | PREPSMN1; SMN2HTTARCA12 | |
| SCHEMBL8068299 | 0.78 | ADORA2A (0.56) | ADORA2ASMN1; SMN2L3MBTL1CA9NPC1 | |
| SCHEMBL30315883 | 0.78 | KDM4E (0.55) | PREPLMNASMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |