Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FER | P16591 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25114487 | 0.86 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DAURKA | |
| SCHEMBL23029798 | 0.83 | SSTR4 (0.42) | L3MBTL1RXFP1MAPT | |
| SCHEMBL31055986 | 0.83 | KDM4E (0.42) | LCKL3MBTL1MAPTKMT2ASLC22A12 | |
| SCHEMBL2030923 | 0.82 | GAA (0.36) | L3MBTL1RXFP1MAPTKMT2A | |
| SCHEMBL17590179 | 0.82 | F2 (0.37) | PTK2L3MBTL1RXFP1MAPTKMT2A | |
| SCHEMBL24857365 | 0.79 | SSTR4 (0.40) | SRCL3MBTL1KMT2A | |
| SCHEMBL2033695 | 0.79 | ALDH1A1 (0.35) | MAPTKMT2A | |
| SCHEMBL24857582 | 0.79 | KDR (0.35) | RETKDRL3MBTL1 | |
| SCHEMBL2010586 | 0.78 | HSP90AA1 (0.34) | PTK2IRAK4L3MBTL1MAPTKMT2A | |
| SCHEMBL2033886 | 0.76 | KDM4E (0.43) | L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |