Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056247 | 0.82 | FOLH1 (0.43) | SIRT1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31056681 | 0.82 | HTR2C (0.44) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL31056082 | 0.81 | KDM1A (0.45) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL31056266 | 0.81 | HTR2C (0.46) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL8408319 | 0.78 | SLC6A4 (0.52) | HTR2CSMN1; SMN2RAB9APTPN1CCR5 | |
| SCHEMBL23700093 | 0.78 | HTR2C (0.47) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL589281 | 0.78 | HTR2C (0.50) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL31562268 | 0.76 | MAPT (0.45) | HTR2CSLC6A4HTR2BKDM1AHTR1A | |
| SCHEMBL23700129 | 0.76 | HTR2C (0.48) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A | |
| SCHEMBL27756953 | 0.76 | HTR2C (0.46) | HTR2CHTR2ASIRT1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |