Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056825 | 0.82 | MCL1 (0.47) | FOLH1MCL1ALDH1A1KDM4EPOLB | |
| SCHEMBL31056166 | 0.82 | HTR2C (0.41) | ALDH1A1L3MBTL1SIRT1MEN1KMT2A | |
| SCHEMBL31056217 | 0.82 | FOLH1 (0.48) | FOLH1MCL1ALDH1A1KDM4EPOLB | |
| SCHEMBL31056459 | 0.82 | FOLH1 (0.45) | FOLH1MCL1ALDH1A1KDM4EPOLB | |
| SCHEMBL31056045 | 0.82 | PTGER1 (0.50) | FOLH1MCL1ALDH1A1KDM4EPOLB | |
| SCHEMBL31056250 | 0.77 | PTGER1 (0.48) | POLBPTGER1MEN1KMT2A | |
| SCHEMBL31056819 | 0.77 | FOLH1 (0.40) | FOLH1MCL1ALDH1A1KDM4EPOLB | |
| Lithium Ion SCHEMBL31056412 | 0.76 | RXRA (0.42) | MCL1ALDH1A1L3MBTL1PTGER1MEN1 | |
| SCHEMBL31056151 | 0.75 | P4HTM (0.48) | FOLH1MCL1KDM4EPTGER1MEN1 | |
| SCHEMBL31562268 | 0.73 | MAPT (0.45) | ALDH1A1KDM4EPOLBL3MBTL1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |