Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15718583 | 0.78 | HPGD (0.64) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL15594368 | 0.78 | KMT2A (0.68) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL31692494 | 0.78 | HTT (0.64) | ABL1KMT2AMEN1GAAMAPT | |
| SCHEMBL26090416 | 0.78 | ALDH1A1 (0.55) | KMT2AMEN1ERN1POLBMAPT | |
| SCHEMBL29954097 | 0.78 | ALDH1A1 (0.54) | KMT2AMEN1GAAMAPTHPGD | |
| SCHEMBL25767955 | 0.77 | KDM4E (0.55) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL24251859 | 0.76 | KMT2A (0.54) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL22393793 | 0.76 | AAK1 (0.49) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL13279699 | 0.75 | ABL1 (0.47) | AAK1ABL1KMT2AMEN1GAA | |
| SCHEMBL31642971 | 0.75 | KMT2A (0.48) | AAK1ABL1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |