Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 17/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319337 | 0.84 | ERN1 (0.54) | ERN1PRKDCCA1CA2 | |
| SCHEMBL5881501 | 0.79 | ERN1 (0.53) | ERN1PRKDCCA1CA2MAPT | |
| SCHEMBL30646113 | 0.78 | ERN1 (0.53) | ERN1LMNAMAPT | |
| SCHEMBL5143316 | 0.78 | ERN1 (0.51) | ERN1PRKDCCA1CA2LMNA | |
| SCHEMBL9787541 | 0.77 | ERN1 (0.48) | ERN1CA1CA2LMNAMAPT | |
| SCHEMBL28678695 | 0.77 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL29365717 | 0.77 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL20562487 | 0.77 | PRKDC (0.47) | ERN1PRKDCCA1CA2LMNA | |
| SCHEMBL30665106 | 0.77 | PRKDC (0.47) | ERN1PRKDCCA1CA2LMNA | |
| SCHEMBL12143391 | 0.75 | ERN1 (0.47) | ERN1PRKDCCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |