Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881501 | 0.87 | ERN1 (0.53) | ERN1PRKDCCA2CA1CA4 | |
| SCHEMBL5143316 | 0.86 | ERN1 (0.51) | ERN1PRKDCCA2CA1TPMT | |
| SCHEMBL31056347 | 0.84 | ERN1 (0.50) | ERN1PRKDCCA2CA1 | |
| SCHEMBL13079432 | 0.81 | ERN1 (0.56) | ERN1CA2CA1TRIM24TYR | |
| SCHEMBL28576504 | 0.80 | ERN1 (0.52) | ERN1PRKDC | |
| SCHEMBL13605932 | 0.79 | PRKDC (0.48) | ERN1PRKDCCA2CA1CA4 | |
| SCHEMBL7004928 | 0.79 | ERN1 (0.67) | ERN1PRKDC | |
| SCHEMBL27500332 | 0.79 | ERN1 (0.54) | ERN1CA2CA1 | |
| SCHEMBL12143391 | 0.79 | ERN1 (0.47) | ERN1PRKDCCA2CA1TPMT | |
| SCHEMBL8007892 | 0.78 | ERN1 (0.50) | ERN1PRKDCCA2CA1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |