Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096893 | 0.84 | DGAT1 (0.41) | NPC1DGAT1F2RL1 | |
| SCHEMBL25770427 | 0.84 | ESR1 (0.40) | NPC1DGAT1 | |
| SCHEMBL31357995 | 0.82 | NPC1 (0.37) | NPC1DGAT1 | |
| SCHEMBL31056563 | 0.81 | NPC1 (0.33) | NPC1DGAT1 | |
| SCHEMBL31055904 | 0.80 | NPC1 (0.36) | NPC1DGAT1 | |
| SCHEMBL31358117 | 0.79 | NPC1 (0.37) | NPC1DGAT1 | |
| SCHEMBL31056473 | 0.78 | NPC1 (0.32) | NPC1DGAT1 | |
| SCHEMBL16023365 | 0.78 | NPC1 (0.42) | NPC1DGAT1 | |
| SCHEMBL31562253 | 0.77 | DGAT1 (0.33) | NPC1DGAT1F2RL1 | |
| SCHEMBL31358136 | 0.76 | BRD4 (0.35) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |