Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568198 | 0.95 | NPC1 (0.59) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL7131857 | 0.86 | APOBEC3A (0.48) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL1280419 | 0.85 | ALDH1A1 (0.54) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL743303 | 0.85 | MEN1 (0.46) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL10867730 | 0.84 | NPC1 (0.43) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL3687116 | 0.82 | ALDH1A1 (0.49) | NPC1ALDH1A1RAB9APARP2MAPT | |
| SCHEMBL31056512 | 0.81 | APOBEC3A (0.52) | NPC1APOBEC3AAPOBEC3GALDH1A1MAPT | |
| SCHEMBL27892679 | 0.80 | APOBEC3A (0.55) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| SCHEMBL17185312 | 0.80 | APOBEC3A (0.61) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL27966304 | 0.80 | NPC1 (0.46) | NPC1APOBEC3AAPOBEC3GALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |