SCHEMBL31056597

SCHEMBL31056597

COC(=O)c1ccc(C2CN(CC(F)F)CCN2Cc2c(OC)cc(C)c3c2ccn3C(=O)OC(C)(C)C)cc1NC(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CFB P00751 18/20 0.38
PDE4B Q07343 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29320356 1.00 CFB (0.38) CFBPDE4B
SCHEMBL31056727 0.95 CFB (0.38) CFB
SCHEMBL29324363 0.95 CFB (0.38) CFB
SCHEMBL31056830 0.95 CFB (0.38) CFB
SCHEMBL29324362 0.95 CFB (0.38) CFB
SCHEMBL31056670 0.95 CFB (0.38) CFB
SCHEMBL31056679 0.94 CFB (0.38) CFB
SCHEMBL31056887 0.94 CFB (0.38) CFB
SCHEMBL31056432 0.94 CFB (0.38) CFB
SCHEMBL29323252 0.94 CFB (0.38) CFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148274-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2024-07-11 WO disclosed