Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326532 | 1.00 | BUB1 (0.35) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL16336927 | 0.85 | BUB1 (0.37) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL18487465 | 0.84 | BUB1 (0.38) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL24077259 | 0.84 | KMT2A (0.36) | USP30PRMT5WDR77AAK1MEN1 | |
| SCHEMBL21652828 | 0.77 | BUB1 (0.38) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL30951333 | 0.77 | BUB1 (0.36) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL29326541 | 0.77 | BUB1 (0.36) | BUB1USP30PKMNR1H2UCHL1 | |
| SCHEMBL31056574 | 0.77 | BUB1 (0.36) | BUB1USP30PKMNR1H2UCHL1 | |
| SCHEMBL715654 | 0.77 | BRD4 (0.39) | BUB1USP30PRMT5WDR77AAK1 | |
| SCHEMBL30606423 | 0.77 | BRD4 (0.39) | BUB1USP30PRMT5WDR77AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |