Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056574 | 1.00 | BUB1 (0.36) | BUB1NR1H2KMT2AMEN1NPC1 | |
| SCHEMBL16337908 | 0.82 | BUB1 (0.37) | BUB1KMT2AACLYCYP1A2BCHE | |
| SCHEMBL18486750 | 0.81 | BUB1 (0.39) | BUB1KMT2AMEN1NPC1HTT | |
| SCHEMBL12700349 | 0.81 | KMT2A (0.42) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL23292085 | 0.80 | BUB1 (0.38) | BUB1KMT2AMEN1NPC1HTT | |
| SCHEMBL30557232 | 0.80 | BUB1 (0.38) | BUB1KMT2AMEN1NPC1HTT | |
| SCHEMBL31056884 | 0.77 | BUB1 (0.35) | BUB1NR1H2KMT2AMEN1EED | |
| SCHEMBL29326532 | 0.77 | BUB1 (0.35) | BUB1NR1H2KMT2AMEN1EED | |
| SCHEMBL2381706 | 0.76 | NR4A2 (0.42) | KMT2AMEN1HTTCYP1A2CYP2C19 | |
| SCHEMBL758764 | 0.76 | ACLY (0.47) | BUB1NR1H2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |