Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25258588 | 1.00 | PRKCI (0.42) | PRKCIDAOMAPK1AXL | |
| SCHEMBL30503678 | 0.75 | KDM4E (0.35) | DAO | |
| SCHEMBL18614442 | 0.75 | AXL (0.42) | PRKCIDAOAXL | |
| SCHEMBL5394 | 0.75 | KDM4E (0.35) | DAO | |
| SCHEMBL17546638 | 0.75 | CCR1 (0.40) | — | |
| Water SCHEMBL5968353 | 0.73 | KDM4E (0.34) | — | |
| SCHEMBL17545818 | 0.71 | — | — | |
| SCHEMBL28083103 | 0.69 | KDM4E (0.41) | PRKCIDAOMAPK1AXL | |
| SCHEMBL21856245 | 0.68 | MAPK1 (0.52) | PRKCIDAOMAPK1AXL | |
| SCHEMBL29506191 | 0.68 | MAPK1 (0.52) | PRKCIDAOMAPK1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488944-A | Nitrogen-containing heterocyclic compound having Nrf2 activation | 中外制药株式会社 | 2024-08-13 | — | — | CN | disclosed |