Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241695 | 0.89 | SHMT1 (0.62) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL14098693 | 0.81 | MAPT (0.60) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL20241665 | 0.81 | SHMT1 (0.65) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL31578841 | 0.81 | MEN1 (0.50) | MAPTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL8847666 | 0.81 | MAPT (0.53) | MAPTSMN1; SMN2KMT2AMEN1CYP2C9 | |
| SCHEMBL30163400 | 0.80 | MAPT (0.56) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL20241545 | 0.80 | MAPT (0.56) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL20241893 | 0.80 | KMT2A (0.51) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL20241846 | 0.79 | MAPT (0.55) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 | |
| SCHEMBL20241746 | 0.78 | MAPT (0.54) | MAPTSMN1; SMN2KMT2AMEN1SHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |