Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 17/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.39 |
| ▸ | BID | P55957 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30154391 | 0.93 | BCL2A1 (0.44) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL23323052 | 0.92 | BCL2 (0.46) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL30658683 | 0.92 | BCL2 (0.46) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL30313985 | 0.85 | BCL2 (0.47) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL24854062 | 0.85 | BCL2 (0.44) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL30415477 | 0.81 | BCL2 (0.55) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL23323413 | 0.81 | BCL2 (0.55) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL25204580 | 0.80 | BCL2 (0.47) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL31697992 | 0.80 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL1702063 | 0.80 | BCL2 (0.50) | BCL2BCL2L1BCL2A1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929689-B | Bcl-2 inhibitors | 百济神州有限公司 | 2024-08-27 | — | — | CN | disclosed |