SCHEMBL31697992

SCHEMBL31697992

COC(=O)c1ccc(N2CCC3(CC2)CC2(C3)OCCCO2)cc1Oc1cnc2[nH]ccc2c1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 20/20 0.45
BCL2L1 Q07817 12/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30658683 0.88 BCL2 (0.46) BCL2BCL2L1
SCHEMBL23323052 0.88 BCL2 (0.46) BCL2BCL2L1
SCHEMBL30415477 0.85 BCL2 (0.55) BCL2BCL2L1
SCHEMBL23323413 0.85 BCL2 (0.55) BCL2BCL2L1
SCHEMBL1702063 0.81 BCL2 (0.50) BCL2BCL2L1
SCHEMBL19867786 0.81 BCL2 (0.50) BCL2BCL2L1
SCHEMBL31058008 0.80 BCL2 (0.43) BCL2BCL2L1
SCHEMBL28839728 0.80 BCL2 (0.51) BCL2BCL2L1
SCHEMBL25204580 0.79 BCL2 (0.47) BCL2BCL2L1
SCHEMBL24005913 0.78 BCL2 (0.48) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320208-A1 Intermediates of Sonrotoclax and the Method of Preparing the Same BEONE MEDICINES I GMBH (CH) 2025-10-16 US disclosed
US-20250320207-A1 Ketal Protected Intermediate for Sonrotoclax and Preparation Method Thereof BEONE MEDICINES I GMBH (CH) 2025-10-16 US disclosed
US-20250320208-A1 Intermediates of Sonrotoclax and the Method of Preparing the Same BEONE MEDICINES I GMBH (CH) 2025-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320207-A1 Ketal Protected Intermediate for Sonrotoclax and Preparation Method Thereof KCNH3, KCNH1, KCNH2 BCL2 468/4885BCL2L1 991/4885
US-20250320208-A1 Intermediates of Sonrotoclax and the Method of Preparing the Same DNMT1, UQCRC2, TOP2B BCL2 250/4885BCL2L1 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.