SCHEMBL31058271

SCHEMBL31058271

C1CCC(CCN2CCOCC2)NC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
HTR1A P08908 2/20 0.39
HTR2A P28223 2/20 0.39
KCNH2 Q12809 2/20 0.39
HTR1D P28221 1/20 0.39
HRH1 P35367 1/20 0.39
ADRA1B P35368 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KEAP1 Q14145 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP2D6 P10635 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
MLNR O43193 1/20 0.37
ABCB11 O95342 1/20 0.37
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8333360 0.85 CYP1A2 (0.46) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL10326175 0.84 HTR1A (0.50) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL10326397 0.84 HTR1A (0.50) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL8562869 0.84 HTR1A (0.50) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL7961057 0.83 CYP1A2 (0.48) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL4454573 0.83 CYP1A2 (0.48) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL5683177 0.83 CYP1A2 (0.48) CYP1A2HTR1AHTR2AKCNH2HTR1D
Hydrochloric Acid SCHEMBL11144978 0.82 HTR1A (0.49) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL27980795 0.81 CXCR4 (0.51) CYP1A2HTR1AHTR2AKCNH2HTR1D
SCHEMBL18183309 0.80 HTR1A (0.40) CYP1A2HTR1AHTR2AKCNH2HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175450-A1 SUBSTITUTED S-ALANINATE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2024-08-29 WO disclosed