SCHEMBL31058366

SCHEMBL31058366

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(Nc4cccc(-c5ccc6ccccc6c5)c4)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDK2 Q15119 2/20 0.42
CNR1 P21554 1/20 0.40
MAPT P10636 3/20 0.37
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
OPRK1 P41145 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
CSNK2A1 P68400 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27309907 1.00 ALDH1A1 (0.44) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL16017141 0.93 ALDH1A1 (0.46) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL16017111 0.91 PDK2 (0.42) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL29907923 0.90 PDK2 (0.48) ALDH1A1PDK2CNR1MAPTMEN1
SCHEMBL15677718 0.90 PDK2 (0.48) ALDH1A1PDK2CNR1MAPTMEN1
SCHEMBL15677716 0.88 ALDH1A1 (0.53) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL30455829 0.88 ALDH1A1 (0.53) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL22182348 0.87 PDK2 (0.46) ALDH1A1PDK2CNR1MAPTMEN1
SCHEMBL22920962 0.86 ALDH1A1 (0.42) ALDH1A1CYP3A4HPGDHSD17B10PDK2
SCHEMBL23697143 0.86 ALDH1A1 (0.49) ALDH1A1CYP3A4HPGDHSD17B10PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118488943-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-08-13 CN disclosed