Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321744 | 1.00 | AAK1 (0.35) | AAK1PSMB1PSMB5TSHRALDH1A1 | |
| SCHEMBL25321749 | 1.00 | AAK1 (0.35) | AAK1PSMB1PSMB5TSHRALDH1A1 | |
| SCHEMBL31362889 | 0.89 | AAK1 (0.37) | AAK1PSMB1PSMB5FPR2 | |
| SCHEMBL31058394 | 0.86 | AAK1 (0.40) | AAK1PSMB1PSMB5FPR2 | |
| SCHEMBL25318426 | 0.86 | AAK1 (0.40) | AAK1PSMB1PSMB5FPR2 | |
| SCHEMBL25318429 | 0.86 | AAK1 (0.40) | AAK1PSMB1PSMB5FPR2 | |
| SCHEMBL30550753 | 0.84 | HTR2C (0.36) | PSMB1PSMB5APLNR | |
| SCHEMBL25320682 | 0.84 | HTR2C (0.36) | PSMB1PSMB5APLNR | |
| SCHEMBL25320684 | 0.84 | HTR2C (0.36) | PSMB1PSMB5APLNR | |
| SCHEMBL25319630 | 0.80 | PSMB1 (0.40) | AAK1PSMB1PSMB5FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |