Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153243 | 0.82 | CA12 (0.58) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL29241812 | 0.81 | CA12 (0.56) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL2165918 | 0.80 | CA12 (0.60) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL29153233 | 0.79 | CA12 (0.55) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL30022843 | 0.79 | CA12 (0.55) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL17434592 | 0.79 | CA12 (0.55) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL12559818 | 0.79 | CA12 (0.55) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL20563183 | 0.78 | CA12 (0.48) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL12472033 | 0.77 | CA9 (0.47) | CA12CA9F11AKR1B1DAO | |
| SCHEMBL20660801 | 0.77 | CA12 (0.56) | CA12CA9F11AKR1B1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024152743-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏柯菲平医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |