Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 9/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026255 | 0.89 | XPO1 (0.38) | XPO1PIM1PIM2SIGMAR1MCHR1 | |
| SCHEMBL31026267 | 0.85 | KDM4E (0.38) | XPO1PIM1PIM2SIGMAR1AURKA | |
| SCHEMBL31026276 | 0.84 | BACE1 (0.34) | PIM1PIM2SIGMAR1 | |
| SCHEMBL31026251 | 0.83 | XPO1 (0.38) | XPO1PIM1PIM2MCHR1CTSC | |
| SCHEMBL31026273 | 0.82 | XPO1 (0.37) | XPO1PIM1PIM2MCHR1CTSC | |
| SCHEMBL31026247 | 0.82 | XPO1 (0.37) | XPO1MCHR1CTSC | |
| SCHEMBL31026280 | 0.81 | XPO1 (0.35) | XPO1PIM1PIM2MCHR1CTSC | |
| SCHEMBL31026275 | 0.81 | XPO1 (0.36) | XPO1PIM1PIM2MCHR1CTSC | |
| SCHEMBL30603859 | 0.79 | AURKA (0.54) | AURKACTSC | |
| SCHEMBL29110578 | 0.79 | AURKA (0.54) | AURKACTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024152743-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏柯菲平医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |