Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 5/20 | 0.33 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058639 | 0.81 | XPO1 (0.38) | XPO1CTSCPIM1PIM2MCHR1 | |
| SCHEMBL31026255 | 0.80 | XPO1 (0.38) | XPO1PIM1PIM2MAPTRAB9A | |
| SCHEMBL31026251 | 0.79 | XPO1 (0.38) | XPO1CTSCPIM1PIM2NPC1 | |
| SCHEMBL31026267 | 0.78 | KDM4E (0.38) | XPO1PIM1PIM2NPC1RAB9A | |
| SCHEMBL31026247 | 0.76 | XPO1 (0.37) | XPO1CTSCMCHR1 | |
| SCHEMBL31026269 | 0.73 | XPO1 (0.42) | XPO1PIM1PIM2NPC1RAB9A | |
| SCHEMBL31026271 | 0.72 | XPO1 (0.39) | XPO1CTSCPIM1PIM2NPC1 | |
| SCHEMBL31026263 | 0.72 | XPO1 (0.38) | XPO1PIM1PIM2NPC1RAB9A | |
| SCHEMBL31026273 | 0.71 | XPO1 (0.37) | XPO1CTSCPIM1PIM2NPC1 | |
| SCHEMBL31026253 | 0.71 | XPO1 (0.37) | XPO1PIM1PIM2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635942-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Carephar Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024152743-A1 | QUINOLINE DERIVATIVE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏柯菲平医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118373771-A | Quinoline derivative compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 江苏柯菲平医药股份有限公司 | 2024-07-23 | — | — | CN | disclosed |