Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968467 | 0.81 | TACR1 (0.36) | PARP1TACR1MC4RMC5R | |
| SCHEMBL28304239 | 0.80 | NR1H2 (0.50) | NR1H2NR1H3PARP1KMT2AUSP30 | |
| SCHEMBL5119466 | 0.79 | PARP1 (0.38) | NR1H2NR1H3PARP1TACR1KMT2A | |
| SCHEMBL31556646 | 0.78 | NR1H2 (0.53) | NR1H2NR1H3PARP1UCHL1 | |
| SCHEMBL30442305 | 0.76 | PARP1 (0.40) | NR1H2NR1H3PARP1TACR1USP30 | |
| SCHEMBL31408651 | 0.76 | PARP1 (0.41) | NR1H2NR1H3PARP1TACR1KMT2A | |
| SCHEMBL1769797 | 0.76 | TACR1 (0.43) | TACR1 | |
| SCHEMBL30873752 | 0.75 | TACR1 (0.43) | NR1H2PARP1TACR1 | |
| SCHEMBL5333905 | 0.75 | HTR2C (0.47) | NR1H2NR1H3PARP1 | |
| SCHEMBL27747418 | 0.75 | NR1H2 (0.38) | NR1H2NR1H3PARP1TACR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703792-B | Tricycle derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-08-13 | — | — | CN | disclosed |