Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779264 | 1.00 | CHRM4 (0.49) | CHRM4CREBBPKDM4E | |
| SCHEMBL23779341 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL31058698 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL23779255 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL31058699 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL23779349 | 0.87 | CHRM4 (0.47) | CHRM4 | |
| SCHEMBL31058693 | 0.87 | CHRM4 (0.47) | CHRM4 | |
| SCHEMBL31058683 | 0.82 | CHRM4 (0.52) | CHRM4KDM4E | |
| SCHEMBL23779303 | 0.82 | CHRM4 (0.52) | CHRM4KDM4E | |
| SCHEMBL20602407 | 0.80 | CHRM4 (0.63) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873467-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2024-08-28 | — | — | EP | claimed |