Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | TTK | P33981 | 12/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779303 | 1.00 | CHRM4 (0.52) | CHRM4TTKKDM4EKITFFAR1 | |
| SCHEMBL23779255 | 0.91 | CHRM4 (0.51) | CHRM4TTKKDM4E | |
| SCHEMBL31058698 | 0.91 | CHRM4 (0.51) | CHRM4TTKKDM4E | |
| SCHEMBL23779341 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL31058699 | 0.91 | CHRM4 (0.51) | CHRM4KDM4E | |
| SCHEMBL23779399 | 0.89 | CHRM4 (0.49) | CHRM4TTK | |
| SCHEMBL31058695 | 0.89 | CHRM4 (0.49) | CHRM4TTK | |
| SCHEMBL31058677 | 0.82 | CHRM4 (0.49) | CHRM4KDM4E | |
| SCHEMBL23779264 | 0.82 | CHRM4 (0.49) | CHRM4KDM4E | |
| SCHEMBL20602323 | 0.81 | CHRM4 (0.65) | CHRM4TTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873467-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2024-08-28 | — | — | EP | claimed |