Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.30 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317064 | 1.00 | HRH3 (0.31) | HRH3ACACBGPR119IMPDH2SETD7 | |
| SCHEMBL23305874 | 0.85 | HDAC3 (0.30) | — | |
| SCHEMBL25070634 | 0.82 | KDM4E (0.32) | HRH3ACACBGPR119IMPDH2 | |
| SCHEMBL23317404 | 0.80 | NAMPT (0.37) | HRH3GPR119 | |
| SCHEMBL31059165 | 0.80 | NAMPT (0.37) | HRH3GPR119 | |
| SCHEMBL31059139 | 0.80 | ACACB (0.35) | HRH3ACACBGPR119IMPDH2 | |
| SCHEMBL31059155 | 0.80 | ACACB (0.34) | HRH3ACACBGPR119IMPDH2 | |
| SCHEMBL23317472 | 0.80 | ACACB (0.35) | HRH3ACACBGPR119IMPDH2 | |
| SCHEMBL23317063 | 0.80 | ACACB (0.34) | HRH3ACACBGPR119IMPDH2 | |
| SCHEMBL23317062 | 0.79 | ACACB (0.33) | HRH3ACACBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929709-B | Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors | 比奥根MA公司 | 2024-08-30 | — | — | CN | disclosed |