Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317404 | 1.00 | NAMPT (0.37) | NAMPTGPR119IDO1KDM1AHRH3 | |
| SCHEMBL31059130 | 0.85 | NAMPT (0.40) | NAMPTGPR119 | |
| SCHEMBL23317039 | 0.85 | NAMPT (0.40) | NAMPTGPR119 | |
| SCHEMBL23305078 | 0.83 | TRPM8 (0.38) | KMT2A | |
| SCHEMBL19852543 | 0.82 | GPR119 (0.45) | GPR119IDO1KDM1AHRH3JAK2 | |
| SCHEMBL23317063 | 0.80 | ACACB (0.34) | GPR119HRH3MEN1KMT2AHDAC8 | |
| SCHEMBL23317472 | 0.80 | ACACB (0.35) | GPR119HRH3HDAC8 | |
| SCHEMBL25070634 | 0.80 | KDM4E (0.32) | GPR119IDO1HRH3 | |
| SCHEMBL23317064 | 0.80 | HRH3 (0.31) | GPR119HRH3 | |
| SCHEMBL31059155 | 0.80 | ACACB (0.34) | GPR119HRH3MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929709-B | Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors | 比奥根MA公司 | 2024-08-30 | — | — | CN | disclosed |