Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.44 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | CCNK | O75909 | 3/20 | 0.42 |
| ▸ | CDK9 | P50750 | 3/20 | 0.42 |
| ▸ | CCND3 | P30281 | 2/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805881 | 0.91 | KDM4E (0.41) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805866 | 0.90 | MAPT (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805737 | 0.89 | NPC1 (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805683 | 0.88 | MAPT (0.53) | CCNA2CDK2CCNKCDK9NPC1 | |
| SCHEMBL23534111 | 0.87 | CTSC (0.46) | LRRK2ALKMET | |
| SCHEMBL29805884 | 0.86 | CSNK1D (0.47) | NPC1RAB9AMAPTOPRK1SMN1; SMN2 | |
| SCHEMBL29805848 | 0.86 | ZAP70 (0.46) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL26617109 | 0.83 | ALK (0.54) | CDK9ALK | |
| SCHEMBL31059280 | 0.83 | CCNA2 (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805882 | 0.82 | CCNA2 (0.47) | CCNA2CDK2CCNKCDK9CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |