Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 9/20 | 0.47 |
| ▸ | CDK2 | P24941 | 9/20 | 0.47 |
| ▸ | CCNK | O75909 | 7/20 | 0.46 |
| ▸ | CDK9 | P50750 | 7/20 | 0.46 |
| ▸ | CCND3 | P30281 | 6/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29806018 | 0.85 | KDR (0.46) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL23533953 | 0.83 | EGFR (0.57) | CDK9ALK | |
| SCHEMBL31059290 | 0.83 | CCNA2 (0.44) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805881 | 0.82 | KDM4E (0.41) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805866 | 0.80 | MAPT (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29806050 | 0.80 | CCNA2 (0.59) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805737 | 0.79 | NPC1 (0.47) | CCNA2CDK2CCNKCDK9CCND3 | |
| SCHEMBL29805683 | 0.79 | MAPT (0.53) | CCNA2CDK2CCNKCDK9KDM4E | |
| SCHEMBL23534111 | 0.78 | CTSC (0.46) | ALKLRRK2 | |
| SCHEMBL29806090 | 0.78 | ULK1 (0.51) | CCNA2CDK2CCNKCDK9CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | claimed |
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |