SCHEMBL31060076

SCHEMBL31060076

Cc1cc(I)cc(C(N)=O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.45
MALT1 Q9UDY8 2/20 0.35
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
NTRK1 P04629 2/20 0.34
NPC1 O15118 1/20 0.33
GRM4 Q14833 1/20 0.31
CHRNA7 P36544 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060035 0.92 DHODH (0.41) DHODHMALT1SMN1; SMN2NTRK1
SCHEMBL10028767 0.91 DHODH (0.45) DHODHMALT1RAB9ANTRK1NPC1
SCHEMBL29377193 0.91 DHODH (0.44) DHODHMALT1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL15984455 0.91 DHODH (0.44) DHODHMALT1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31060097 0.91 DHODH (0.44) DHODHMALT1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL29215156 0.90 DHODH (0.38) DHODHMALT1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31060047 0.89 DHODH (0.40) DHODHMALT1NTRK1GRM4MEN1
SCHEMBL13662273 0.89 DHODH (0.37) DHODHMALT1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17238835 0.89 DHODH (0.43) DHODHMALT1RAB9ASMN1; SMN2NPC1
SCHEMBL10028768 0.89 DHODH (0.43) DHODHMALT1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 DHODH 90/4885MALT1 2427/4885RAB9A 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.