Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 11/20 | 0.73 |
| ▸ | AURKA | O14965 | 7/20 | 0.73 |
| ▸ | JAK3 | P52333 | 6/20 | 0.73 |
| ▸ | JAK2 | O60674 | 6/20 | 0.73 |
| ▸ | IGF1R | P08069 | 3/20 | 0.73 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.73 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.73 |
| ▸ | RET | P07949 | 2/20 | 0.73 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.73 |
| ▸ | FLT3 | P36888 | 2/20 | 0.73 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.73 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
| ▸ | FYN | P06241 | 1/20 | 0.73 |
| ▸ | FLT1 | P17948 | 1/20 | 0.73 |
| ▸ | LTK | P29376 | 1/20 | 0.73 |
| ▸ | KDR | P35968 | 1/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.73 |
| ▸ | CLK2 | P49760 | 1/20 | 0.73 |
| ▸ | CDK7 | P50613 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434985 | 1.00 | NTRK1 (0.73) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL18281508 | 1.00 | NTRK1 (0.73) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL588730 | 1.00 | NTRK1 (0.73) | NTRK1AURKAJAK3JAK2IGF1R | |
| Phosphoric Acid SCHEMBL3041888 | 0.95 | NTRK1 (0.66) | NTRK1AURKAJAK3JAK2IGF1R | |
| Maleic Acid SCHEMBL4904780 | 0.93 | NTRK1 (0.63) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL3034183 | 0.92 | NTRK1 (0.71) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL3041951 | 0.91 | NTRK1 (0.69) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL17433341 | 0.91 | NTRK1 (0.59) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL588783 | 0.89 | JAK3 (0.57) | NTRK1AURKAJAK3JAK2IGF1R | |
| SCHEMBL3036561 | 0.89 | JAK2 (0.58) | NTRK1AURKAJAK3JAK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |