Pr-104

Pr-104

SCHEMBL31060232

CS(=O)(=O)OCCN(CCBr)c1c(C(=O)NCCOP(=O)(O)O)cc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 4/20 0.33
RAB9A P51151 1/20 0.32
LMNA P02545 3/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
HTT P42858 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PRMT5 O14744 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pr-104 SCHEMBL367963 1.00 KMT2A (0.36) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL13338201 0.92 TDP1 (0.38) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL3422264 0.92 KMT2A (0.36) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL3418938 0.92 KMT2A (0.36) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL3589344 0.91 KMT2A (0.40) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL13338135 0.90 KMT2A (0.38) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL366334 0.90 KMT2A (0.38) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL29468020 0.90 KMT2A (0.38) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL3420379 0.90 MEN1 (0.33) KMT2AMEN1HPGDNPSR1NPC1
SCHEMBL13338209 0.88 KMT2A (0.36) KMT2AMEN1HPGDNPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed