SCHEMBL31060469

SCHEMBL31060469

Cc1ccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 18/20 1.00
HDAC1 Q13547 15/20 1.00
HDAC2 Q92769 2/20 1.00
NCOR2 Q9Y618 2/20 1.00
HDAC8 Q9BY41 1/20 1.00
HDAC4 P56524 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529065 1.00 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1938496 1.00 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1937829 0.99 HDAC3 (0.98) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1938110 0.88 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1938122 0.88 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1938221 0.88 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1937223 0.88 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL16011065 0.88 HDAC4 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1937932 0.88 HDAC3 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8
SCHEMBL1937980 0.88 HDAC1 (1.00) HDAC3HDAC1HDAC2NCOR2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed