Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 1.00 |
| ▸ | PDGFRA | P16234 | 12/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 1.00 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | CDK7 | P50613 | 1/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060290 | 0.81 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRKDM4EESR2 | |
| SCHEMBL31060586 | 0.81 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL31061185 | 0.75 | PDGFRB (1.00) | PDGFRBPDGFRAGAK | |
| SCHEMBL2346887 | 0.74 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL14906701 | 0.74 | PDGFRB (0.62) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL14905366 | 0.74 | PDGFRB (0.58) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL31060338 | 0.74 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL31060653 | 0.72 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL26560487 | 0.72 | PDGFRB (0.70) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL29403027 | 0.71 | PDGFRB (0.61) | PDGFRBPDGFRAEGFRESR2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |