Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 1.00 |
| ▸ | PDGFRA | P16234 | 11/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060586 | 0.75 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAPK10KDM4E | |
| SCHEMBL31060871 | 0.72 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRMAPK10KDM4E | |
| SCHEMBL14905366 | 0.68 | PDGFRB (0.58) | PDGFRBPDGFRAEGFRMAPK10KDM4E | |
| SCHEMBL28176909 | 0.67 | PDGFRB (0.50) | PDGFRBPDGFRAEGFRKMT2AESR2 | |
| SCHEMBL23884462 | 0.67 | MEN1 (0.52) | PDGFRBPDGFRAKDM4EMEN1ALDH1A1 | |
| SCHEMBL31463343 | 0.67 | LMNA (0.58) | PDGFRBPDGFRAEGFRKDM4ECYP3A4 | |
| SCHEMBL31463342 | 0.67 | LMNA (0.58) | PDGFRBPDGFRAEGFRKDM4ECYP3A4 | |
| SCHEMBL12179667 | 0.67 | PDGFRB (0.59) | PDGFRBPDGFRAEGFRMAPK10KDM4E | |
| SCHEMBL4309282 | 0.66 | MAPK10 (1.00) | PDGFRBPDGFRAEGFRMAPK10MEN1 | |
| SCHEMBL31060989 | 0.66 | PDGFRB (1.00) | PDGFRBPDGFRAKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |