Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 12/20 | 1.00 |
| ▸ | PIM1 | P11309 | 10/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844464 | 1.00 | PIM3 (1.00) | PIM3PIM1PIM2TDP2MEN1 | |
| SCHEMBL844520 | 0.88 | PIM3 (0.78) | PIM3PIM1PIM2ALDH1A1CYP2A6 | |
| SCHEMBL844940 | 0.87 | PIM3 (0.76) | PIM3PIM1PIM2ALDH1A1CYP2A6 | |
| SCHEMBL844836 | 0.79 | PIM3 (0.70) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL845204 | 0.79 | PIM3 (0.70) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL879300 | 0.78 | PIM3 (0.71) | PIM3PIM1PIM2MEN1ALDH1A1 | |
| SCHEMBL844605 | 0.78 | PIM3 (0.64) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL844328 | 0.76 | PIM3 (0.61) | PIM3PIM1PIM2TDP2MEN1 | |
| SCHEMBL845188 | 0.75 | PIM3 (0.60) | PIM3PIM1PIM2ALDH1A1KDM4E | |
| SCHEMBL10079034 | 0.74 | PIM3 (0.71) | PIM3PIM1PIM2ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |