Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383954 | 1.00 | HPGD (0.47) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL1383105 | 0.84 | CDK5 (0.39) | HPGDMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1386055 | 0.82 | CCR4 (0.38) | MAPTKMT2AHSD11B1L3MBTL1NPC1 | |
| Bromide SCHEMBL6507724 | 0.80 | LMNA (0.40) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL1383097 | 0.78 | LMNA (0.51) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL6501525 | 0.77 | TSHR (0.43) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL1604395 | 0.74 | LMNA (0.47) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL1604478 | 0.73 | LMNA (0.46) | HPGDLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5016459 | 0.71 | LMNA (0.44) | HPGDLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL20899953 | 0.69 | TAAR1 (0.40) | LMNAMAPTKMT2AMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |