Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 1.00 |
| ▸ | PLK4 | O00444 | 3/20 | 1.00 |
| ▸ | PLK1 | P53350 | 3/20 | 1.00 |
| ▸ | RET | P07949 | 1/20 | 1.00 |
| ▸ | FLT3 | P36888 | 1/20 | 1.00 |
| ▸ | KDR | P35968 | 1/20 | 0.72 |
| ▸ | PIM1 | P11309 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | SNCA | P37840 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CTRC | Q99895 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470603 | 1.00 | PDGFRB (1.00) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL29666461 | 1.00 | PDGFRB (1.00) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL5470607 | 1.00 | PDGFRB (1.00) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL16442341 | 1.00 | PDGFRB (1.00) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL1301398 | 0.86 | PDGFRB (0.76) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL29875506 | 0.86 | PDGFRB (0.76) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL247890 | 0.86 | PDGFRB (0.76) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL247891 | 0.86 | PDGFRB (0.76) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL3569608 | 0.85 | PLK4 (0.74) | PDGFRBPLK4PLK1RETFLT3 | |
| SCHEMBL3569611 | 0.85 | PLK4 (0.74) | PDGFRBPLK4PLK1RETFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |