Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 1.00 |
| ▸ | LCK | P06239 | 3/20 | 1.00 |
| ▸ | KDR | P35968 | 8/20 | 0.73 |
| ▸ | RET | P07949 | 1/20 | 0.73 |
| ▸ | KIF5B | P33176 | 1/20 | 0.73 |
| ▸ | BRAF | P15056 | 5/20 | 0.65 |
| ▸ | RAF1 | P04049 | 4/20 | 0.61 |
| ▸ | CSF1R | P07333 | 1/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | FLT4 | P35916 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182199 | 1.00 | EGFR (1.00) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL20229657 | 0.85 | KDR (0.74) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL13680204 | 0.85 | KDR (0.73) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL15463614 | 0.84 | KDR (0.73) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL1012448 | 0.84 | KDR (0.73) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL31060791 | 0.84 | KDR (1.00) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL6181628 | 0.84 | EGFR (0.72) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL15463602 | 0.83 | EGFR (0.71) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL18158553 | 0.82 | KDR (0.70) | EGFRLCKKDRRETKIF5B | |
| SCHEMBL23457663 | 0.82 | LCK (0.74) | EGFRLCKKDRRETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |